Bryson reacts to the Bills beating the Patriots 24-10 and why it is yet another sign that Bill Belichick and Mac Jones are the issue in New England as well as why last night was a great sign for Buffalo offensively. He then predicts the biggest college football games on championship weekend and what the College Football Playoff will be by Selection Sunday, followed by his predictions for Sunday's Week 13 NFL action including his Upset of the Week, If I Were a Bettin' Man, and his new segment, Bryson's Bleak Bet!